ACT - Adaptive Collaborative Treatments

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“The world of innovation out there is significantly increasing survival and quality of life for many people – this should not just be for the privileged few, this should be for everyone. That is our mission.”

Baroness Tessa Jowell

Film credit: The Guardian. Tessa Jowell: Former Labour MP delivers moving speech on brain cancer diagnosis. January 2018. (

ACT (Adaptive Collaborative Treatments) is a cancer organisation founded by the late Baroness Tessa Jowell, her daughter Jess Mills and Dr Jack Kreindler.

ACT's goal is to make 'Adaptive Trials' of personalised combination therapies an option for all patients with untreatable cancers.

We have already started, with the UK Department of Health led £65m Dame Tessa Jowell Brain Cancer Research Mission, bringing together the Brain Tumour Charity, 13 NHS Brain Cancer centres, CRUK, NIHR, the Eliminate Cancer Initiative and many more.

Our goal is to build the first 'National Grid for Smart Trials and ACTs'. Adaptive Collaborative Treatment should become a standard option in all advanced and incurable cancers, supported by a network of trained patient advocates, where the prognosis is poor and access to breakthrough drug trials is not available.

ACT's mission is to deliver more hope to patients and their loved ones, support and tools for their doctors, and new data to medical science. Everyone has been touched in some way by cancer. We need your help and to work together to make this possible and accessible to all.

One in two people are now being affected by cancer in their lifetime. With your support we can help people live well with cancer, not just die from it.

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Baroness Tessa Jowell & Jess Mills

Baroness Tessa Jowell and Jess Mills
Co-founders, ACT for Cancer

In May 2017, Baroness Tessa Jowell was diagnosed with Glioblastoma. Since project managing her mother’s care, Jess Mills, the musician daughter of Baroness Tessa Jowell, is now campaigning to transform the way cancer patients can access the most innovative treatments available through the NHS. Jess is campaigning for global collaboration between doctors to improve patient care, global sharing of data and to make the most innovative treatments available to everyone in the UK, irrespective of income or access.

Dr. Jack Kreindler

Dr Jack Kreindler
Co-founder, ACT for Cancer

Dr Jack Kreindler is a close family friend of Baroness Tessa Jowell and Jess Mills, and is also a co-founder of ACT for Cancer. In 2014, Dr Jack Kreindler began exploring the application of machine learning to medical imaging in the US. His work is now leading the way in the early detection of lung cancer. Through his London-based Centre for Health and Human Performance (CHHP) and his organisation in the US, he is encouraging start-ups to build tests that can give early markers of changes before they manifest themselves as cancer.

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